Strengthening the resilience of vulnerable households, communities and systems is central to achieving food security and improving nutrition in contexts affected by shocks and stressors. The Rome-based Agencies (RBA) developed a joint Conceptual Framework - “Strengthening Resilience for Food Security and Nutrition” - to work more and better together, and with key partners, to strengthen resilience of the most food-insecure. A set of joint country case studies - Guatemala, Kenya and Niger - explore ongoing efforts and future opportunities for greater collaboration among the RBA agencies on building resilience.